| Background: | p14ARF is a human tumor suppressor protein associated with the CDK4/pRB and p53 pathways. p14ARF acts by inhibiting cyclin-dependent kinases, and it can induce both G1 and G2 arrest via its stabilizing effects on the p53 transcrIPPtion factor. p14ARF and its mouse homologue, p19ARF, are also involved in cellular senescence and apoptosis. |
| Clonality: | Monoclonal |
| Clone Number: | DCS-240 |
| Formulation: | 0.2 mg/mL in PBS/1% BSA/10% glycerol/0.09% sodium azide |
| Gene ID Human: | 1029 |
| Gene ID Mouse: | 12578 |
| Host Species: | Mouse |
| Immunogen: | Recombinant fulll length Human p14ARF |
| Regulatory Statement: | For Research Use Only. Not for use in diagnostic procedures. |
| Isotype: | IgG1 |
| Product Type: | Primary Antibody |
| Shipping: | 4 |
| Size: | 10 µg |
| Species Reactivities: | Human |
| Status: | RUO |
| Storage: | 4℃ |
| Target: | p14ARF |
Applications: IP, WB
| IPP: | 3 μg/300 μL of cell extract 3 x 106 cel |
| WB: | 1-5 μg/mL |
There are no references for Anti-p14ARF (Human) mAb at this time.