Solutions for Life Science & Diagnostics
Anti-p21WAF1/CIP1 (Human) mAb
Additional Information
Anti-p21WAF1/CIP1 (Human) mAb Specifications
| Background: | p21WAF1/CIPP1 is one member of the CIPP/KIPP family that controls the cell cycle by inhibiting cyclin dependent kinases (CDKs) activity. Increased expression of p21WAF1/CIPP1 may play an important role in the growth arrest induced in transformed cells. It is reported that hypermethylation of the p21WAF1/CIPP1 promoter region inactivate p21WAF1/CIPP1 gene leading tumorigenesis, and also reported that p21WAF1/CIPP1 acts as an inhibitor of apoptosis in a number of systems in addition to being an inhibitor of cell proliferation. |
| Clonality: | Monoclonal |
| Clone Number: | DCS-60 |
| Formulation: | 1.0 mg/mL in PBS/50% glycerol, pH 7.2 |
| Gene ID Human: | 1026 |
| Gene ID Mouse: | 12575 |
| Host Species: | Mouse |
| Immunogen: | Recombinant Human fulll length p21WAF1/CIP1 |
| Regulatory Statement: | For Research Use Only. Not for use in diagnostic procedures. |
| Isotype: | IgG2a |
| Product Type: | Primary Antibody |
| Shipping: | 4 |
| Size: | 100 μg |
| Species Reactivities: | Human |
| Status: | RUO |
| Storage: | -20℃ |
| Target: | p21/WAF1 |
Applications: IH, IP, WB
| IHC: | 1-5 ug/mL (Heat treatment is necessary for paraffi |
| IPP: | 3 ug/200-300 uL of cell extract |
| WB: | 1-5 ug/mL (for chemiluminescence detection system) |
There are no references for Anti-p21WAF1/CIP1 (Human) mAb at this time.
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