Solutions for Life Science & Diagnostics
Anti-p18INK4c (Human) mAb
Additional Information
Anti-p18INK4c (Human) mAb Specifications
| Background: | The INK4 family of proteins consists of four members that block progression from the G1-to-S phase of the cell cycle by inhibiting the activity of Cdk4 and Cdk6. The p18INK4c cyclin-dependent kinase inhibitor is an important regulator of cellular differentiation and cell cycle progression, and it also acts as a potent tumor suppressor. p18INK4c is regulated by the transcrIPPtion factors E2F1 and SP1 in response to environmental and intracellular signals such as cytokines, oncogenic overload, or cellular senescence. |
| Clonality: | Monoclonal |
| Clone Number: | DCS-118 |
| Formulation: | 0.2 mg/mL in PBS/1% BSA/10% glycerol/0.1% sodium azide |
| Gene ID Human: | 1031 |
| Gene ID Mouse: | 12580 |
| Host Species: | Mouse |
| Immunogen: | Recombinant fulll length Human p18INK4c |
| Regulatory Statement: | For Research Use Only. Not for use in diagnostic procedures. |
| Isotype: | IgG2a |
| Product Type: | Primary Antibody |
| Shipping: | 4 |
| Size: | 10 µg |
| Species Reactivities: | Human |
| Status: | RUO |
| Storage: | 4℃ |
| Target: | p18INK4c |
Applications: IH, IP, WB
| IHC: | 1-5 μg/mL (Heat treatment is necessary for paraffi |
| IPP: | 3 μg/200-300 μL of cell extract from 5x106 |
| WB: | 1 μg/mL |
There are no references for Anti-p18INK4c (Human) mAb at this time.
Product Images
