Angiogenesis
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Product Catalog |
p18INK4c Monoclonal Antibody : Trial SizeCode No: K0079-3S
Target:
p18INK4c Background:
The INK4 family of proteins consists of four members that block progression from the G1-to-S phase of the cell cycle by inhibiting the activity of Cdk4 and Cdk6. The p18INK4c cyclin-dependent kinase inhibitor is an important regulator of cellular differentiation and cell cycle progression, and it also acts as a potent tumor suppressor. p18INK4c is regulated by the transcrIPPtion factors E2F1 and SP1 in response to environmental and intracellular signals such as cytokines, oncogenic overload, or cellular senescence.
Size:
10 µg
Application:
WB
Application:
IPP
Application:
IHC
Clone Number:
DCS-118
Concentration:
0.2 mg/mL
Product Type:
Primary Antibody
Host Species:
Mouse
Species Reactivities:
Human
Isotype:
IgG2a
Storage Temp. (°C):
4
Shipping Temp. (°C):
4 References:
1) Thullberg, M., et al., FEBS Letters 470, 161-166 (2000) Formulation:
10 g IgG in 50 L volume of PBS containing 1% BSA, 10% glycerol and 0.1% sodium azide as preservative. Sodium azide has been reported to form potentially explosive lead or copper azide in plumbing. To prevent forming of these compounds, flush drains enough after disposing of solutions containing sodium azide.
Reactivity:
This antibody reacts with human p18INK4c.
Intended Use:
For Research use only. Not for use in diagnostic procedure. |
