- Diagnostic Products
- Research Products
|Background:||Human Pleiotrophin (PTN) also called HARP (Heparin affin regulatory peptide) is a new member of the heparin-binding neurotrophic factor family. PTN (Pleiotrophin) and MK (midkine) are structural homologs, and are highly conserved among species. Pleiotrophin is a growth factor involved in the differentiation and proliferation of neuronal tissue during embryogenesis, and also secreted by melanoma and breast carcinoma cells. Pleiotrophin exhibits mitogenic and angiogenic properties and has been shown to influence the vascular supply, expansion and metastasis of tumor cells. Recombinant human PTN is a 15.4 kDa protein, comprising of 136 amino acid residues.|
|Regulatory Statement:||For Research Use Only. Not for use in diagnostic procedures.|
There are no references for Human NT-4 at this time.