Solutions for Life Science & Diagnostics
JNK Polyclonal Antibody
Additional Information
JNK Polyclonal Antibody Specifications
| Background: | The JNK (c-Jun N-terminal Kinase) pathway is activated by largely distinct stimuli including inflammatory cytokines (such as TNF-ï¡ and IL-1), UV light, inhibitors of protein synthesis and osmotic stress. Activated MEKK1 phosphorylates SEK1 (also known as MKK4), which in turn activates SAPK (stress-activated protein kinase, also known as JNK). JNK binds tightly to the N-terminal region of c-Jun and ATF-2, and phosphorylates c-Jun at Ser63 and Ser73 and ATF-2 at Thr69 and Thr71. |
| Clonality: | Polyclonal |
| Host Species: | Rabbit |
| Regulatory Statement: | For Research Use Only. Not for use in diagnostic procedures. |
| Isotype: | IgG |
| Product Type: | Primary Antibody |
| Shipping: | 4 |
| Size: | 100 µg |
| Species Reactivities: | H,M,R |
| Status: | RUO |
| Storage: | -20 |
| Target: | JNK |
Applications: WB, IP, IH
There are no references for JNK Polyclonal Antibody at this time.
