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JIP-1 (JNK Interacting Protein 1) Polyclonal Antibody

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SKUNameSizeQtyPriceAdd to Cart
JM-3664-100 JIP-1 (JNK Interacting Protein 1) Polyclonal Antibody 100 ug $294.00

Additional Information

JIP-1 (JNK Interacting Protein 1) Polyclonal Antibody Specifications

Background:JIP1 (JNK-interacting protein-1) is a cytoplasmic protein that possesses an N-terminal JNK-binding domain and a C-terminal SRC homology 3 (SH3) domain. JIP1 selectively bind to JNK, but not to the ERK or p38 MAP kinases. In addition to JNK, JIP1 binds to specific proteins of JNK pathways, including MKK7, MLK3, and DLK, all at separate binding sites. JIP1 has been identified in brain and kidney tissues, whereas JIP2a, JIP2b, and JIP3 are specifically expressed in the brain. Overexpression of JIP1 causes cytoplasmic retention of JNK, thereby preventing its nuclear accumulation and the subsequent activation of the JNK pathways, indicating that JIP1 acts as a cytoplasmic anchor for JNK.
Clonality:polyclonal
Host Species:Rabbit
Regulatory Statement:For Research Use Only. Not for use in diagnostic procedures.
Isotype:IgG
Product Type:Primary Antibody
Shipping:4
Size:100 ug
Species Reactivities:M,R
Status:RUO
Storage:-20
Target:JIP-1 (JNK Interacting 1)

Applications: WB

There are no references for JIP-1 (JNK Interacting Protein 1) Polyclonal Antibody at this time.