Solutions for Life Science & Diagnostics

MMP-12 Polyclonal Antibody

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SKUNameSizeQtyPriceAdd to Cart
JM-3532R-100 MMP-12 Polyclonal Antibody 100 µg $288.75

Additional Information

MMP-12 Polyclonal Antibody Specifications

Background:The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, fibronectin, laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. MMP-12 (also designated macrophage metalloelastase) is produced in alveolar macrophages and degrades elastin. MMP-12 may contribute to elastin degradation occurring in granulomatous skin diseases and may also participate in macrophage migration through the epidermal and vascular basement membranes in inflammatory disorders.
Clonality:Polyclonal
Host Species: Rabbit
Regulatory Statement:For Research Use Only. Not for use in diagnostic procedures.
Isotype:IgG
Product Type:Primary Antibody
Shipping:4
Size:100 µg
Species Reactivities:H
Status:RUO
Storage:-20
Target:MMP-12

Applications: WB, IP, IH

There are no references for MMP-12 Polyclonal Antibody at this time.