| Background: | Lck is a membrane associated tyrosine protein kinases. The Lck gene has been shown to undergo rearrangement and over-expression in some murine lymphomas. In human studies, it has been demonstrated that the Lck gene is localized to a site in the genome which undergoes frequent chromosomal abnormalities in lymphomas and neuroblastomas. Resting T cells contain high levels of the Lck protein and mRNA both of which decline upon activation of the T cells. These and other observations suggest that alterations in Lck expression may contribute to the pathogenesis of some types of neoplastic disease. |
| Clonality: | Polyclonal |
| Host Species: | Rabbit |
| Regulatory Statement: | For Research Use Only. Not for use in diagnostic procedures. |
| Isotype: | IgG |
| Product Type: | Primary Antibody |
| Shipping: | 4 |
| Size: | 100 ug |
| Species Reactivities: | H |
| Status: | RUO |
| Storage: | -20 |
| Target: | Lck |
Applications: WB, IP, IH
There are no references for Lck Polyclonal Antibody at this time.