- Diagnostic Products
- Research Products
|Background:||Lck is a membrane associated tyrosine protein kinases. The Lck gene has been shown to undergo rearrangement and over-expression in some murine lymphomas. In human studies, it has been demonstrated that the Lck gene is localized to a site in the genome which undergoes frequent chromosomal abnormalities in lymphomas and neuroblastomas. Resting T cells contain high levels of the Lck protein and mRNA both of which decline upon activation of the T cells. These and other observations suggest that alterations in Lck expression may contribute to the pathogenesis of some types of neoplastic disease.|
|Regulatory Statement:||For Research Use Only. Not for use in diagnostic procedures.|
|Product Type:||Primary Antibody|
Applications: WB, IP, IH
There are no references for Lck Polyclonal Antibody at this time.