Solutions for Life Science & Diagnostics
Bax Monoclonal Antibody
Additional Information
Bax Monoclonal Antibody Specifications
| Background: | The Bcl-2 (B-cell leukemia/lymphoma 2) family proteins function to either inhibit (Bcl-2 and Bcl-XL) or promote (Bax and Bak) apoptosis. Similar to other family member, Bax contains the conserved Bcl-2 homology 1 (BH1) and 2 (BH2) domains which allow for its homodimerization or heterodimerization with Bcl-2. The ratio of Bax homodimers to Bax/Bcl-2 heterodimers is an apoptotic checkpoint. When Bcl-2 is in excess, apoptosis is inhibited. However, if Bax levels increase in response to a death signal, the cell is pushed toward death. Bax has three different isoforms, which are Bax-ï¡, ï¢, and ï§. The 21 kDa Bax-ï¡ is the most common form in most cells and tissues. |
| Clonality: | Monoclonal |
| Clone Number: | 6036A7 |
| Host Species: | Mouse |
| Regulatory Statement: | For Research Use Only. Not for use in diagnostic procedures. |
| Isotype: | IgG |
| Product Type: | Primary Antibody |
| Shipping: | 4 |
| Size: | 100 µg |
| Species Reactivities: | H,M,R |
| Status: | RUO |
| Storage: | -20 |
| Target: | Bax |
Applications: WB
There are no references for Bax Monoclonal Antibody at this time.
