Solutions for Life Science & Diagnostics
caspase-9 (Active) Polyclonal Antibody
Additional Information
caspase-9 (Active) Polyclonal Antibody Specifications
| Background: | Caspases are synthesized as inactive pro-enzymes that are processed to active form in cells undergoing apoptosis. Caspase-9 is an important member of the caspase family. Upon induction of apoptosis, Cytochrome c released from mitochondria associates with pro-caspase-9 (47 kDa) and Apaf-1. The complex processes pro-caspase-9 into a large subunit (37 kDa/17 kDa) and a small subunit (10 kDa). Cleaved caspase-9 further processes other caspases including caspase-3 and caspase-6, to initiate a caspase cascade leading to apoptosis. The affinity purified antibody recognizing the active forms of caspase-9 provides a new tool for identifying apoptotic cell populations in both tissue sections and cultured cells. |
| Clonality: | Polyclonal |
| Host Species: | Rabbit |
| Regulatory Statement: | For Research Use Only. Not for use in diagnostic procedures. |
| Isotype: | IgG |
| Product Type: | Primary Antibody |
| Shipping: | 4 |
| Size: | 100 µg |
| Species Reactivities: | R |
| Status: | RUO |
| Storage: | -20 |
| Target: | caspase-9 |
Applications: WB, IH
There are no references for caspase-9 (Active) Polyclonal Antibody at this time.
