Solutions for Life Science & Diagnostics
Rabbit Anti-AURORA B Polyclonal Antibody
Additional Information
Rabbit Anti-AURORA B Polyclonal Antibody Specifications
| Background: | Human aurora A (aurora related kinase-1 (ARK-1), Aik1, STK15, BTAK, aurora2), and human aurora B (aurora related kinase-2 (ARK-2), Aik2, STK12, aurora1) are centrosome-associated serine/threonine kinases that regulate centrosome separation, bIPPolar spindle assembly, and chromosome segregation during mitosis.1, 2 Aurora B has unique genetic loci relative to Aurora A suggesting that these two kinases, with oncogenic potential, have different roles in cell cycle progression.1, 3 Aurora B exists in a complex with surviving and inner centromere protein (INCENP) in mitosis, and its kinase activity is stimulated by surviving binding and cell cycle-dependent phosphorylation.4 Phosphorylation of INCENP by aurora B stimulates aurora B kinase activity.5 |
| Clonality: | Polyclonal |
| Host Species: | Rabbit |
| Regulatory Statement: | For Research Use Only. Not for use in diagnostic procedures. |
| Isotype: | IgG |
| Product Type: | Primary Antibody |
| Shipping: | 4 |
| Size: | 100 UG |
| Species Reactivities: | H |
| Status: | RUO |
| Storage: | -20 |
| Target: | Rabbit AURORA B |
Applications: WB, IP, IF
There are no references for Rabbit Anti-AURORA B Polyclonal Antibody at this time.
