Solutions for Life Science & Diagnostics
Anti-Phospho-Chk1 (Ser345) mAb
Additional Information
Anti-Phospho-Chk1 (Ser345) mAb Specifications
| Background: | Chk1 is one of the key regulators of DNA damage checkpoint. In response to damaged DNA or stalled replication, ATR phosphorylates Chk1 at Ser-317 and Ser-345; This phosphorylation is considered to elevate the catalytic activity of Chk1. Activated Chk1 can |
| Clonality: | Monoclonal |
| Clone Number: | #83-4-43 |
| Formulation: | PBS/50% glycerol, pH 7.2 |
| Gene ID Human: | 1111 |
| Gene ID Mouse: | 12649 |
| Host Species: | Rat |
| Immunogen: | KLH conjugated synthetic peptide, QGISFpSQPTCP |
| Regulatory Statement: | For Research Use Only. Not for use in diagnostic procedures. |
| Isotype: | IgG2b |
| Product Type: | Primary Antibody |
| Shipping: | 4 |
| Size: | 100 ug/100 uL |
| Source: | Purified IgG from hybridoma supernatant |
| Species Reactivities: | Human, Mouse |
| Status: | RUO |
| Storage: | -20℃ |
| Target: | Chk1 |
Applications: IC, IP, WB
| ICC: | 1 μg/mL |
| IPP: | 6 μg/1.2 mL of cell extract from 1.2 x 107 |
| WB: | Reference 1 (1 μg/mL) |
There are no additional documents for Anti-Phospho-Chk1 (Ser345) mAb at this time.
1) Kasahara, K., et al., EMBO J. 29, 2802-2812 (2010) [WB, IC] 2) Chen, M. S., et al., Mol. Cell Biol. 23, 7488-7497 (2003) 3) Jin, J., et al., Genes Dev. 17, 3062-3074 (2003) 4) Jiang, K., et al., J. Biol. Chem. 278, 25207-25217 (2003) 5) Zou, L. and Ell
