Solutions for Life Science & Diagnostics
Anti-CD61 (GPIIIa) (Human) mAb-Alexa Fluor® 647
Additional Information
Anti-CD61 (GPIIIa) (Human) mAb-Alexa Fluor® 647 Specifications
| Background: | Glycoprotein IIIa, a ï¢3 (CD61) subunit of integrin ï¡IIbï¢3 (CD41/CD61), acts as a fibrinogen receptor on the platelet surface. A mouse monoclonal antibody, T74, recognizes human ï¢3 (CD61) subunit and inhibits platelet aggregation induced by several agonists such as collagen, ADP, and thrombin. T74 inhibits clot-retraction mediated by platelets or ï¡vï¢3-expressing cells when induced by thrombin. Western-blot analysis is not possible. T74 fails to bind to platelets from patients with Glanzmann’s thrombasthenia. |
| Clonality: | Monoclonal |
| Clone Number: | T74 |
| Conjugate: | Alexa Fluor® 647 |
| Formulation: | 1 mg/mL in PBS/1% BSA/0.1% sodium azide |
| Host Species: | Mouse |
| Immunogen: | Human thrombocyte |
| Regulatory Statement: | For Research Use Only. Not for use in diagnostic procedures. |
| Isotype: | IgG2a κ |
| Product Type: | Primary Antibody |
| Shipping: | 4 |
| Size: | 50 uL/50ug |
| Species Reactivities: | Human |
| Status: | RUO |
| Storage: | 4℃ |
| Target: | CD61 |
Applications: FCM
| FCM: | 1 μg/mL (final concentration) |
There are no references for Anti-CD61 (GPIIIa) (Human) mAb-Alexa Fluor® 647 at this time.
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