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CD62P-Alexa647

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Code No: D280-A64
Datasheet: 
application/pdf iconD280-A64_anti-CD62P-Alexa647_ver.1.1.pdf
FID:12023 | PATH:sites/default/files/datasheets/D280-A64_anti-CD62P-Alexa647_ver.1.1.pdf
Target: 

CD62P

Background: 

CD62P, a platelet granule membrane protein (GMP-140), is a member of the selectin family. Since CD62P is expressed by the platelet surface on platelet activation, it is also known as the platelet activation-dependent granule-external membrane protein (PADGEM). CD62P interacts with PSGL-1 (CD162), which mediates the rolling of leukocytes on the surface of activated endothelial cells, the first step in leukocyte extravasation and migration towards inflammations. A monoclonal antibody, 2T60, recognizes both human and rabbit CD62P. In experimental cerebral thrombosis of rabbits, 2T60 detects activated platelets adhering to the damaged subendothelium and thrombi.

Size: 
50 uL/50ug
Application: 
FCM
Conjugate: 
Alexa647
Product Type: 
Primary Antibody
Species Reactivities: 
Human
Storage Temp. (°C): 
4
Shipping Temp. (°C): 
4
Pictures: 
CD62P-Alexa647
Related Products: 

D274-3 CD42b (TM60) D274-A48 CD42b-Alexa Fluor®488 (TM60) D274-A64 CD42b-Alexa Fluor®647 (TM60) D276-3 CD36 (GS95) D276-A48 CD36-Alexa Fluor®488 (GS95) D276-A64 CD36-Alexa Fluor®647 (GS95) D280-3 CD62P (2T60) D280-A48 CD62P-Alexa Fluor®488 (2T60) D280-A64 CD62P-Alexa Fluor®647 (2T60) D281-3 CD61 (T74) D281-A48 CD61-Alexa Fluor®488 (T74) D281-A64 CD61-Alexa Fluor®647 (T74) PD033 Anti-1-Tubulin (polyclonal) M109-3 Mouse CD61 (1-55-4) IM-0409 CD42b (SZ2) IM-0648 CD42b-FITC (SZ2) IM-1417 CD42b-PE (SZ2) IM-2116 CD61 (SZ21) IM-0540 CD61 (SZ21) IM-1758 CD61-FITC (SZ21) IM-3605 CD61-PE (SZ21) IM-3716 CD61-PC7 (SZ21) IM-0765 CD36 (FA6.152) IM-0766 CD36-FITC (FA6.152) IM-1315 CD62P (CLBThromb/6) A07790 CD62P-FITC (CLBThromb/6) IM-1759 CD62P-PE (CLBThromb/6) MTG-001 Clear Back M075-3 Mouse IgG1 isotype control (2E12) M075-A48 Mouse IgG1 isotype control-Alexa Fluor® 488 (2E12) M075-A64 Mouse IgG1 isotype control-Alexa Fluor® 647 (2E12) M076-3 Mouse IgG2a isotype control (6H3) M076-A48 Mouse IgG2a isotype control-Alexa Fluor® 488 (6H3) M076-A64 Mouse IgG2a isotype control-Alexa Fluor® 647 (6H3)

References: 

1) Burger, P. C., et al., Blood 101, 2661-2666 (2003) 2) Tanoue, K., et al., Platelets 4, 31-39 (1993) 3) McEver, R. P., et al., J. Clin. Invest. 84, 92-99 (1989) 4) Johnston, G. I., et al., Cell 56, 1033-1044 (1989)

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