CD62P

Datasheet:

D280-3_anti-CD62P_ver.1.pdf

Target:

CD62P

Background:

CD62P, a platelet granule membrane protein (GMP-140), is a member of the selectin family. Since CD62P is expressed by the platelet surface on platelet activation, it is also known as the platelet activation-dependent granule-external membrane protein (PADGEM). CD62P interacts with PSGL-1 (CD162), which mediates the rolling of leukocytes on the surface of activated endothelial cells, the first step in leukocyte extravasation and migration towards inflammations. A monoclonal antibody, 2T60, recognizes both human and rabbit CD62P. In experimental cerebral thrombosis of rabbits, 2T60 detects activated platelets adhering to the damaged subendothelium and thrombi.

Size:

100 uL/100ug

Application:

FCM

Product Type:

Primary Antibody

Species Reactivities:

Human

Isotype:

IgG2a κ

Storage Temp. (°C):

-20

Shipping Temp. (°C):

4

Pictures:

Related Products:

D274-3 CD42b (TM60)
D274-A48 CD42b-Alexa Fluor®488 (TM60)
D274-A64 CD42b-Alexa Fluor®647 (TM60)
D276-3 CD36 (GS95)
D276-A48 CD36-Alexa Fluor®488 (GS95)
D276-A64 CD36-Alexa Fluor®647 (GS95)
D280-3 CD62P (2T60)
D280-A48 CD62P-Alexa Fluor®488 (2T60)
D280-A64 CD62P-Alexa Fluor®647 (2T60)
D281-3 CD61 (T74)
D281-A48 CD61-Alexa Fluor®488 (T74)
D281-A64 CD61-Alexa Fluor®647 (T74)
PD033 Anti-1-Tubulin (polyclonal)
M109-3 Mouse CD61 (1-55-4)
IM-0409 CD42b (SZ2)
IM-0648 CD42b-FITC (SZ2)
IM-1417 CD42b-PE (SZ2)
IM-2116 CD61 (SZ21)
IM-0540 CD61 (SZ21)
IM-1758 CD61-FITC (SZ21)
IM-3605 CD61-PE (SZ21)
IM-3716 CD61-PC7 (SZ21)
IM-0765 CD36 (FA6.152)
IM-0766 CD36-FITC (FA6.152)
IM-1315 CD62P (CLBThromb/6)
A07790 CD62P-FITC (CLBThromb/6)
IM-1759 CD62P-PE (CLBThromb/6)
MTG-001 Clear Back
M075-3 Mouse IgG1 isotype control (2E12)
M075-A48 Mouse IgG1 isotype control-Alexa Fluor® 488 (2E12)
M075-A64 Mouse IgG1 isotype control-Alexa Fluor® 647 (2E12)
M076-3 Mouse IgG2a isotype control (6H3)
M076-A48 Mouse IgG2a isotype control-Alexa Fluor® 488 (6H3)
M076-A64 Mouse IgG2a isotype control-Alexa Fluor® 647 (6H3)

References:

1) Burger, P. C., et al., Blood 101, 2661-2666 (2003)
2) Tanoue, K., et al., Platelets 4, 31-39 (1993)
3) McEver, R. P., et al., J. Clin. Invest. 84, 92-99 (1989)
4) Johnston, G. I., et al., Cell 56, 1033-1044 (1989)

Product Catalog

More like this