Solutions for Life Science & Diagnostics
Anti-EpCAM (CD326) (Mouse) mAb
Additional Information
Anti-EpCAM (CD326) (Mouse) mAb Specifications
| Background: | The mouse epithelial adhesion molecule (EpCAM) also known as gp40/CD326/Ly-74 is a 40-42 kDa of cell surface glycoprotein. EpCAM is a calcium-independent homotypic adhesion molecule. It is also expressed in thymic epithelial cells, thymic dendritic cells, peripheral T cells, intestinal epithelium, keratinocytes, lymph node, splenic dendritic cells and tumor-initiating cells. Recently, it is reported that EpCAM and TROP2, which is a member of the EpCAM family, is expressed in mouse hepatic oval cells. TROP2 is upregulated in oval cells raises the possibility that TROP2 modulate and/or enhance the intracellular signaling of EpCAM to promote proliferation and migration into liver parenchyma. The interaction of EpCAM and TROP2 may be involved in oval cell proliferation. |
| Clonality: | Monoclonal |
| Clone Number: | 2-17-F1 |
| Formulation: | 1 mg/mL in PBS/50% glycerol, pH 7.2 |
| Host Species: | Rat |
| Immunogen: | Mouse EpCAM transfected Ba/F3 cells |
| Regulatory Statement: | For Research Use Only. Not for use in diagnostic procedures. |
| Isotype: | IgG2a |
| Product Type: | Primary Antibody |
| Shipping: | 4 |
| Size: | 100 μg / 100 μL |
| Species Reactivities: | Mouse |
| Status: | RUO |
| Storage: | -20℃ |
| Target: | CD326 |
Applications: FCM
| FCM: | 10 μg/mL (final concentration) |
There are no references for Anti-EpCAM (CD326) (Mouse) mAb at this time.
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