Solutions for Life Science & Diagnostics
Anti-JAM-A (Mouse) mAb
Additional Information
Anti-JAM-A (Mouse) mAb Specifications
| Background: | Junctional adhesion molecules (JAMs) are member of the immunoglobulin superfamily. JAMs play an important role in many cellular processes such as tight junction assembly, leukocyte transmigration, platelet activation, angiogenesis and virus binding. JAM-A is a 37 kDa protein also called JAM-1 or F11R. JAM-A is expressed on endothelial cells, epithelial cells, and also hematopoietic cells such as neutrophils, platelets, monocytes, lymphocyte and erythrocyte. Extracellular domain of JAM-A participates in homophilic interaction stabilizing endothelial or epithelial cell-cell junctions particularly around tight junctions. In addition, JAM-A is important in leukocyte transmigration. Not only homophilic JAM-A interactions between leukocytes and the endothelium but also heterophilic interactions of JAM-A with the ï¢2-integrin leukocyte function-associated antigen-1 (LFA-1) are considered to mediate leukocyte transmigration. |
| Clonality: | Monoclonal |
| Clone Number: | 27-9 |
| Formulation: | 1 mg/mL in PBS/50% glycerol, pH 7.2 |
| Gene ID Human: | 478974 |
| Gene ID Mouse: | 16456 |
| Host Species: | Rat |
| Immunogen: | Mouse getal hapatic cells (E14.5) |
| Regulatory Statement: | For Research Use Only. Not for use in diagnostic procedures. |
| Product Type: | Primary Antibody |
| Shipping: | 4 |
| Size: | 100ug |
| Species Reactivities: | Mouse |
| Status: | RUO |
| Storage: | -20℃ |
| Target: | JAM-A |
Applications: FCM, IH
| FCM: | 5 ug/mL (final concentration) |
| IHC: | 10 ug/mL (frozen section) |
There are no references for Anti-JAM-A (Mouse) mAb at this time.
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