Solutions for Life Science & Diagnostics
Anti-Foxp3 (Mouse) mAb?Biotin
Additional Information
Anti-Foxp3 (Mouse) mAb?Biotin Specifications
| Background: | Forkhead-winged helix P3 (Foxp3), also known as Scurfin or JM2, is a 50-55 kDa transcrIPPtion factor, originally identified as the gene defective in Scurfy mice. Scurfy mice and humans with similar mutations spontaneously develop autoimmune diseases (IPPEX). Resent reports revealed that Foxp3 is expressed in CD4+ CD25+ regulatory T cells (Treg cells), and ectopic expression of Foxp3 in CD4+ Foxp3- T cells induced a Treg-like phenotype in these cells. Importantly, these reports indicate that Foxp3 is a specific marker for Treg cells. Taken together, Foxp3 is believed to be a crucial regulator of the development and function of Treg cells. |
| Clonality: | Monoclonal |
| Clone Number: | MF-14 |
| Conjugate: | Biotin |
| Formulation: | 0.2 mg/mL in PBS/1% BSA/0.09% sodium azide |
| Host Species: | Rat |
| Immunogen: | Recombinant Mouse fulll length Foxp3 |
| Regulatory Statement: | For Research Use Only. Not for use in diagnostic procedures. |
| Isotype: | IgG2b |
| Product Type: | Primary Antibody |
| Shipping: | 4 |
| Size: | 20 ug |
| Species Reactivities: | Mouse |
| Status: | RUO |
| Storage: | 4℃ |
| Target: | Foxp3 |
Applications: FCM, IH
| FCM: | 2 ug/mL (final concentration) |
| IHC: | 5 ug/mL (Can be used in cryosections.) |
There are no references for Anti-Foxp3 (Mouse) mAb?Biotin at this time.
