Solutions for Life Science & Diagnostics
Anti-LYVE-1 (Mouse) mAb
Additional Information
Anti-LYVE-1 (Mouse) mAb Specifications
| Background: | Hyaluronan (HA) is a high molecular weight polymer composed of alternating glucuronic acid and N-acetylglucosamine. HA is involved in homeostasis, development, and tissue remodeling. A major receptor for HA is designated as LYVE-1 (Lymphatic vessel endothelial hyaluronan receptor-1). LYVE-1 is a ~35 kDa integral membrane protein which is down-regulated in human liver cancer and cirrhosis. LYVE-1 localizes on the luminal face of the lymph wall, but is absent from blood vessels. Thus, anti-LYVE-1 antibody is a powerful tool for the identification of lymph vessels and for studies of lymphangiogenesis. LYVE-1 antibodies have been used successfully to distinguish lymphatic invasion by malignant tumor cells from blood vessel invasion. |
| Clonality: | Monoclonal |
| Clone Number: | ALY7 |
| Formulation: | 1 mg/mL in PBS/50% glycerol, pH 7.2 |
| Gene ID Human: | 10894 |
| Gene ID Mouse: | 114332 |
| Host Species: | Rat |
| Immunogen: | Recombinant Mouse LYVE-1 extracellular domain (1-228 a.a.) |
| Regulatory Statement: | For Research Use Only. Not for use in diagnostic procedures. |
| Isotype: | IgG1 |
| Product Type: | Primary Antibody |
| Shipping: | 4 |
| Size: | 100 μg |
| Species Reactivities: | Mouse |
| Status: | RUO |
| Storage: | -20℃ |
| Target: | LYVE-1 |
Applications: FCM, IH
| FCM: | 5 μg/mL (final concentration) |
| IHC: | 10 μg/mL (Heat treatment is necessary for paraffin |
There are no references for Anti-LYVE-1 (Mouse) mAb at this time.
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