| Background: | The heterogeneous nuclear ribonucleoprotein-A2/B1 (hnRNP-A2/B1) was recently shown to be up-regulated in the early stage of lung cancer. This protein plays an important role in biogenesis and transport of mRNA. Up-regulation of hnRNP usually precedes morphological differentiation and is considered a good biomarker in the early stages of cancer development. HnRNP-A2/B1 proteins were localized primarily in the nucleus, excluding the nucleolus, although the expression of A2 protein was weaker than that of B1 protein. hnRNP-A2/B1 proteins were apparently expressed in nonmalignant alveolar cells as well as cancer cells, although the expression in alveolar cells was weaker than that of cancer cells. |
| Clonality: | Monoclonal |
| Clone Number: | C20308 |
| Formulation: | 1.0 mg/mL in PBS/50% glycerol, pH 7.2 |
| Gene ID Human: | 3181 |
| Gene ID Mouse: | 53379 |
| Host Species: | Mouse |
| Immunogen: | Protein fraction extracted from the mitotic chromosome |
| Regulatory Statement: | For Research Use Only. Not for use in diagnostic procedures. |
| Isotype: | IgM |
| Product Type: | Primary Antibody |
| Shipping: | 4 |
| Size: | 100 μg |
| Species Reactivities: | Human, Mouse |
| Status: | RUO |
| Storage: | -20℃ |
| Target: | HnRNP-A2/B1 |
Applications: IC, WB
| ICC: | 10 ug/mL |
| WB: | 10 ug/mL (for chemiluminescence detection system) |
There are no references for Anti-hnRNP-A2/B1 mAb at this time.

