Solutions for Life Science & Diagnostics
Anti-CD257 (BAFF/BLyS) (Human) mAb-FITC
Additional Information
Anti-CD257 (BAFF/BLyS) (Human) mAb-FITC Specifications
| Alternative Names: | TNFSF13B; tumor necrosis factor (ligand) superfamily, member 13b |
| Background: | CD257/BAFF (B cell-activating factor belonging to the TNF family) is a membrane protein expressed by dendritic cells, monocytes, macrophages, follicular dendritic cells, activated T cells, activated neutrophils, and malignant B cells. BAFF, also known as BLyS (B lymphocyte stimulator), is a potent B cell growth factor. Proteolytic cleavage can result in the release of a soluble trimeric BAFF which binds to the BAFF receptor, BCMA and TACI. The release of soluble BAFF is regulated by IFN-ï§ and to a lesser extent IL-10. BAFF protects B cells from apoptosis and increases the expression of anti-apoptotic proteins Bcl-2 and Bcl-xL. |
| Clonality: | Monoclonal |
| Clone Number: | 1D6 |
| Conjugate: | FITC |
| Formulation: | 0.5 mg/mL in PBS/1% BSA/0.09% sodium azide |
| Gene ID Human: | 10673 |
| Gene ID Mouse: | 24099 |
| Host Species: | Mouse |
| Immunogen: | Human CD257/BAFF/BLyS transfectant |
| Regulatory Statement: | For Research Use Only. Not for use in diagnostic procedures. |
| Isotype: | IgG1 k |
| Product Type: | Primary Antibody |
| Shipping: | 4 |
| Size: | 50 µg |
| Species Reactivities: | Human |
| Status: | RUO |
| Storage: | 4℃ |
| Target: | BAFF/BLyS |
Applications: FCM
| FCM: | 10μg/mL (final concentration) |
There are no references for Anti-CD257 (BAFF/BLyS) (Human) mAb-FITC at this time.
