Anti-MFG-E8 (Mouse) mAb
Anti-MFG-E8 (Mouse) mAb Specifications
|Alternative Names:||Mfge8; milk fat globule-EGF factor 8 protein|
|Background:||Apoptotic cells are rapidly removed by phagocytosis to clear the living cells and tissues of intracellular materials being released from dying cells. Phagocytes recognize apoptotic cells through milk fat globule-EGF-factor 8 (MFG-E8). MFG-E8 is a secreted glycoprotein from thioglycollate-elicited macrophages and bind to phosphatidylserine exposed on the cell surface of apoptotic cells, then bind strongly to cells expressing avb3 integrin via its RGD (arginine-glycine-aspartate) motif. Thus, MFG-E8 is an important protein to mediate the engulfment of apoptotic cells by activated macrophages.
|Formulation:||1.0 mg/mL in PBS/50% glycerol, pH 7.2|
|Gene ID Human:||4240|
|Gene ID Mouse:||17304|
|Immunogen:||Recombinant Mouse MFG-E8|
|Regulatory Statement:||For Research Use Only. Not for use in diagnostic procedures.|
|Product Type:||Primary Antibody|
Applications: IH, WB
|IHC:||1 ug/mL (Can be used in cryosections.)|
|WB:||1 ug/mL (for chemiluminescence detection system)|
There are no references for Anti-MFG-E8 (Mouse) mAb at this time.