Solutions for Life Science & Diagnostics
Anti-MFG-E8 (Mouse) mAb
Additional Information
Anti-MFG-E8 (Mouse) mAb Specifications
| Alternative Names: | Mfge8; milk fat globule-EGF factor 8 protein |
| Background: | Apoptotic cells are rapidly removed by phagocytosis to clear the living cells and tissues of intracellular materials being released from dying cells. Phagocytes recognize apoptotic cells through milk fat globule-EGF-factor 8 (MFG-E8). MFG-E8 is a secreted glycoprotein from thioglycollate-elicited macrophages and bind to phosphatidylserine exposed on the cell surface of apoptotic cells, then bind strongly to cells expressing avb3 integrin via its RGD (arginine-glycine-aspartate) motif. Thus, MFG-E8 is an important protein to mediate the engulfment of apoptotic cells by activated macrophages. |
| Clonality: | Monoclonal |
| Clone Number: | 18A2-G10 |
| Formulation: | 1.0 mg/mL in PBS/50% glycerol, pH 7.2 |
| Gene ID Human: | 4240 |
| Gene ID Mouse: | 17304 |
| Host Species: | Hamster |
| Immunogen: | Recombinant Mouse MFG-E8 |
| Regulatory Statement: | For Research Use Only. Not for use in diagnostic procedures. |
| Isotype: | IgG |
| Product Type: | Primary Antibody |
| Shipping: | 4 |
| Size: | 100 μg |
| Species Reactivities: | Mouse |
| Status: | RUO |
| Storage: | -20℃ |
| Target: | MFG-E8 |
Applications: IH, WB
| IHC: | 1 ug/mL (Can be used in cryosections.) |
| WB: | 1 ug/mL (for chemiluminescence detection system) |
There are no references for Anti-MFG-E8 (Mouse) mAb at this time.
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