Solutions for Life Science & Diagnostics

Anti-CD93 (Human) mAb

Ordering Guide

SKUNameSizeQtyPriceAdd to Cart
D198-3 Anti-CD93 (Human) mAb 100 μg/100 µL $210.00

Additional Information

Anti-CD93 (Human) mAb Specifications

Alternative Names:C1qRp
Background:CD93, also known as C1qRp, is a 100-125 kDa type I membrane protein that is a receptor for the complement protein C1q. CD93 has also been shown to act as a receptor for mannose-binding lectin and surfactant protein A. CD93 is expressed on the surface of monocytes, granulocytes, and endothelial cells, and expression is increased by TNF-α or GM-CSF. CD93 is involved in ligand-mediated enhancement of phagocytosis and intercellular adhesion.
Clonality:Monoclonal
Clone Number:mNI-11
Conjugate:Unlabeled
Formulation:1 mg/mL in PBS/50% glycerol, pH7.2
Gene ID Human:22918
Host Species:Mouse
Immunogen:LPS-stimulated U937
Regulatory Statement:For Research Use Only. Not for use in diagnostic procedures.
Isotype:IgG1
Product Type:Primary Antibody
Shipping:4
Size:100 μg/100 µL
Species Reactivities:Human
Status:RUO
Storage:-20
Target:CD93

Applications: IPP,FCM,IHC

FCM:5 μg/mL (final concentration)
IHC:10 μg/mL (Can be used in cryosections.)
IPP:2 μg/400 μg of cell extract from 5x106<
Application References:
  1. Ikewaki N et al. Unique properties of cluster of differentiation 93 in the umbilical cord blood of neonates. Microbiol Immunol. 57, 822-32 (2013) (PMID:24033555)
  2. Ikewaki N et al. Decrease in CD93 (C1qRp) expression in a human monocyte-like cell line (U937) treated with various apoptosis-inducing chemical substances. 51, 1189-200 (2007) (PMID:18094537)
  3. Ikewaki N et al. Flow cytometric identification of CD93 expression on naive T lymphocytes (CD4(+)CD45RA (+) cells) in human neonatal umbilical cord blood. J Clin Immunol. 30, 723-733 (2010) (PMID:20512406)
  4. Ikewaki N et al. Regulation of CD93 cell surface expression by protein kinase C isoenzymes. Microbiol Immunol. 50, 93-103 (2006) (PMID:16490927)
  5. McGreal EP et al. Human C1qRp is identical with CD93 and the mNI-11 antigen but does not bind C1q. J Immunol. 15, 5222-32 (2002) (PMID:11994479)Application: FCM
  6. Ikewaki N et al. A unique monoclonal antibody mNI-11 rapidly enhances spread formation in human umbilical vein endothelial cells. J Clin Immunol. 20, 317-24 (2000) (PMID:10939719)
  7. Ikewaki N, Inoko H. Development and characterization of a novel monoclonal antibody (mNI-11) that induces cell adhesion of the LPS-stimulated human monocyte-like cell line U937. J Leukoc Biol. 59, 697-708 (1996) (PMID:8656055)

 

Product Images

Anti-CD93 (Human) mAb