| Background: | In addition to hemostasis and host defense, platelets are involved in the induction of inflammation, tissue repair, and tumor metastasis. Aggrus (T1ï¡/Podoplanin) is a novel 36-45 kDa membrane sialoglycoprotein that induces platelet aggregation. Aggrus is highly expressed in various tumor cells and the platelet aggregation ability of Aggrus depends on specific oligosaccharide structures that may be related to the metastasis process in cancer cells. Aggrus has been identified as a diagnostic tumor marker for seminoma. |
| Clonality: | Monoclonal |
| Clone Number: | YM-1 |
| Formulation: | Prepared from culture supernatant with preservative (0.09% sodium azide) |
| Gene ID Human: | 10630 |
| Gene ID Mouse: | 14726 |
| Host Species: | Rat |
| Immunogen: | Human Aggrus N-terminal peptide (38-51 a.a.) |
| Regulatory Statement: | For Research Use Only. Not for use in diagnostic procedures. |
| Isotype: | IgG2a |
| Product Type: | Primary Antibody |
| Shipping: | 4 |
| Size: | 100 μg |
| Species Reactivities: | Human |
| Status: | RUO |
| Storage: | 4℃ |
| Target: | PDPN |
Applications: FCM, IH, WB
| FCM: | 1:25 |
| IHC: | 1:20 (Can be used in paraffin-embedded sections.) |
| WB: | 1:500 (for chemiluminescence detection system) |
There are no references for Anti-Aggrus (Podoplanin) (Human) mAb at this time.
