Solutions for Life Science & Diagnostics
Anti-CENP-A (Human) mAb
Additional Information
Anti-CENP-A (Human) mAb Specifications
| Background: | Centromere protein A (CENP-A) is a　17-19 kDa centromere-specific histone variant that is 62%　identical to the carboxy-terminal domain of histone H3. In the presence of DNA, CENP-A forms an octameric complex with histones H4, H2A, and H2B. CENP-A defines active centromere regions by forming centromere-specific nucleosomes on which kinetochores are assembled. CENP-A is specifically located to the inner plate of the kinetochore and it is essential for kinetochore targeting of CENP-C and other kinetochore components. CENP-A is required for nucleosomal packaging of centromeric DNA at interphase. |
| Clonality: | Monoclonal |
| Clone Number: | 3-19 |
| Formulation: | 1 mg/mL in PBS/50% glycerol, pH 7.2 |
| Gene ID Human: | 1058 |
| Gene ID Mouse: | 12615 |
| Host Species: | Mouse |
| Immunogen: | Human CENP-A peptide (3-19 aa) |
| Regulatory Statement: | For Research Use Only. Not for use in diagnostic procedures. |
| Isotype: | IgG1 |
| Product Type: | Primary Antibody |
| Shipping: | 4 |
| Size: | 100 μg |
| Species Reactivities: | Human |
| Status: | RUO |
| Storage: | -20℃ |
| Target: | CENP-A |
Applications: IC, IH, WB
| ICC: | 10 ug/mL |
| IHC: | 5 ug/mL (Heat treatment is necessary for paraffin |
| WB: | 1 ug/mL |
| Other: | ChIP* |
There are no references for Anti-CENP-A (Human) mAb at this time.
Product Images
