| Background: | Synaptophysin (also referred to as SVP38 and p38) is an acidic Ca2+ binding glycoprotein of about 38 kDa which exist largely in synaptic vesicles. It has 4 transmembrane regions and is reported to be a major cholesterol-binding protein in synaptic vesicles. Synaptophysin may regulate synaptic exocytosis by competing with proteins such as SNAP25 and syntaxins to bind to synaptobrevin (vesicle-associated membrane protein, or VAMP). It may also participate in synaptic endocytosis, which contributes to rapid recycling of synaptic vesicle. |
| Clonality: | Monoclonal |
| Clone Number: | 171B5 |
| Formulation: | 1.0 mg/mL in PBS/50% glycerol, pH 7.2 |
| Gene ID Human: | 8867 |
| Gene ID Mouse: | 104015 |
| Host Species: | Mouse |
| Immunogen: | purified synaptic vesicle fraction from guinea pig cerebrum |
| Regulatory Statement: | For Research Use Only. Not for use in diagnostic procedures. |
| Isotype: | IgG1 |
| Product Type: | Primary Antibody |
| Shipping: | 4 |
| Size: | 100 μg |
| Species Reactivities: | Human |
| Status: | RUO |
| Storage: | -20℃ |
| Target: | Synaptophysin |
Applications: IH, WB
| IHC: | 10 ug/mL |
| WB: | 1 ug/mL (for chemiluminescence detection system) |
There are no references for Anti-Synaptophysin (Guinea pig) mAb at this time.

