- Diagnostic Products
- Research Products
|Background:||14-3-3 protein family is highly conserved from plants to mammals and ubiquitously expressed cellular proteins. In mammals, there are seven isoforms encoded by a distinct gene (Beta, Epsilon, Gamma, Sigma, Eta, Tau and Zeta). More than 200 target proteins of the 14-3-3 protein family have been identified. Interactions of 14-3-3 proteins and the target proteins are dependent on phosphorylation of serine/threonine residue on the target proteins with some exceptions. 14-3-3 is deeply and widely involved in mitogenic signaling, cell cycle regulation and cell death/survival, suggesting the family plays important role in human neoplastic and neurological diseases.|
|Gene ID Human:||7529|
|Gene ID Mouse:||54401|
|Regulatory Statement:||For Research Use Only. Not for use in diagnostic procedures.|
There are no references for 14-3-3 β (Human) at this time.