Solutions for Life Science & Diagnostics
Anti-Osteopontin pAb
Additional Information
Anti-Osteopontin pAb Specifications
| Background: | Osteopontin (OPN, also designated Bone Sialoprotein 1, Urinary Stone Protein, spp-1, eta-1, nephropontin, uropontin) is an acidic member of the small integrinbinding ligand N-linked glycoprotein (SIBLING) family of extracellular matrix proteins/cytokines that undergoes extensive posttranslational modification, including phosphorylation, glycosylation, and cleavage, yielding molecular mass variants ranging in size from 25 to 75 kDa. The result is a versatile protein(s) with multIPPle functions arising from its role as a mediator of cell-cell and cell-extracellular matrix (ECM) communication that encompass both normal and tumorigenic developmental processes, immunological responses during inflammation and wound healing, and biomineralization. OPN contains a hydrophobic leader sequence characteristic of a secreted protein, a potential calcium phosphate apatite binding region of consecutive asparagine residues, a cell attachment RGD sequence, a thrombin cleavage site, and two glutamines that are recognized substrates for transglutaminase supported multimer formation. |
| Clonality: | Polyclonal |
| Formulation: | 0.5 mg/mL in 10 mM Phosphate Buffer/150 mM NaCl/50% glycerol, pH 7.5 |
| Gene ID Human: | 6696 |
| Gene ID Mouse: | 20750 |
| Host Species: | Rabbit |
| Immunogen: | KSKKFRRPDIQYPDATDE, corresponding to 170-187 a.a. of human Osteopontin isoform a |
| Regulatory Statement: | For Research Use Only. Not for use in diagnostic procedures. |
| Product Type: | Primary Antibody |
| Shipping: | 4 |
| Size: | 100 ug |
| Species Reactivities: | Human |
| Status: | RUO |
| Storage: | -20℃ |
| Target: | Osteopontin |
Applications: IH, WB
| IHC: | 1-3 μg/mL |
| WB: | 0.5-1 μg/mL |
There are no references for Anti-Osteopontin pAb at this time.
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