Solutions for Life Science & Diagnostics
Anti-Phospho-LSP1 (Ser204) mAb
Additional Information
Anti-Phospho-LSP1 (Ser204) mAb Specifications
| Background: | Signal transduction in B lymphocytes following antigen binding to a membrane-associated immunoglobulin complex initiates a diverse array of intracellular events. To define genes participating in these events, May et al. (1993) and others used various cDNA cloning strategies to identify genes preferentially expressed in B lymphocytes. One gene, variously named LSP1 and pp52, has a number of properties supporting a possible role in B-cell signaling pathways. LSP1 (The leukocyte specific protein 1) is a multi functional protein involved in such divers biological processes as the regulation of neutrophil motility, chemotaxis, adhesion and membrane immunoglobulin M (mIgM) mediated apoptosis of B-lymphocytes. The 330-amino-acid mouse LSP1 protein contains a high-affinity F-actin binding site and in intact cells localizes to the F-actin filament containing cytoskeleton. |
| Clonality: | Monoclonal |
| Clone Number: | AT-1E6 |
| Formulation: | 1.0 mg/mL in 10 mM HEPES KOH/150 mM NaCl/50 % glycerol, pH 7.5 |
| Gene ID Human: | 4046 |
| Gene ID Mouse: | 16985 |
| Host Species: | Mouse |
| Immunogen: | a synthetic phophopeptide corresponding to residues surrounding Ser204 of human LSP1 (KLH-conjugated ) |
| Regulatory Statement: | For Research Use Only. Not for use in diagnostic procedures. |
| Isotype: | IgG1 |
| Product Type: | Primary Antibody |
| Shipping: | 4 |
| Size: | 100 μg |
| Species Reactivities: | Human, Mouse, Rat |
| Status: | RUO |
| Storage: | -20℃ |
| Target: | LSP1 |
Applications: ELISA, WB
| ELISA: | 1 μg/mL |
| WB: | 1-2 μg/mL |
There are no references for Anti-Phospho-LSP1 (Ser204) mAb at this time.
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