- Diagnostic Products
- Research Products
|Background:||DUSP1 is a member of a family of dual-specificity phosphatases and contains a highly conserved C-terminal catalytic domain and an N-terminal Cdc25-like (CH2) domain. DUSP1, also known as MKP-1, inactivates MAP kinase by the concomitant dephosphorylation of both its phosphothreonine and phosphotyrosine residues. DUSP1/MKP-1 may play an important role in the human cellular response to environmental stress as well as in the negative regulation of cellular proliferation via the dephosphorylation of MAP kinase. A recent study also shows that DUSP1/MKP-1 is a key factor of major depressive disorder (MDD) and it may be a new drug targets for treating depression and possibly other mood disorders.|
|Regulatory Statement:||For Research Use Only. Not for use in diagnostic procedures.|
There are no references for CycLex Protein Phosphatase DUSP1/MKP-1 (human recombinant, active) at this time.