Solutions for Life Science & Diagnostics
Protein Tyrosine Phosphatase PTPN6/SHP-1 (Human, Active)
Additional Information
Protein Tyrosine Phosphatase PTPN6/SHP-1 (Human, Active) Specifications
| Background: | PTPN6/SHP-1 is expressed at high levels in hematopoietic cells of all lineages and its expression is induced early in hematopoietic differentiation. Insulin stimulates the phosphorylation and activation of PTPN6/SHP-1 by a direct association between PTPN6/SHP-1 and the insulin receptor. PTPN6/SHP-1 plays a crucial role in negatively modulating insulin action and clearance in the liver, thereby regulating whole-body glucose homeostasis. PTPN6/SHP-1 is also reported as a negative regulator in the development of allergic responses such as allergic asthma. |
| Gene ID Human: | 5777 |
| Gene ID Mouse: | 15170 |
| Regulatory Statement: | For Research Use Only. Not for use in diagnostic procedures. |
| Product Type: | Protein |
| Shipping: | dry ice |
| Size: | 50 µg |
| Species Reactivities: | Human |
| Status: | RUO |
| Storage: | -70℃ |
| Target: | PTPN6/SHP |
Applications:
There are no references for Protein Tyrosine Phosphatase PTPN6/SHP-1 (Human, Active) at this time.
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