| Background: | PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. Receptor-type tyrosine-protein phosphatase alpha (PTPRA) contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic protein tyrosine phosphatase (PTPase) domains. PTPRA has been shown to dephosphorylate and activate Src family tyrosine kinases, and is implicated in the regulation of integrin signaling, cell adhesion and proliferation. PTPRA has been also shown to interact with Grb2 and KCNA2. |
| Gene ID Human: | 5786 |
| Gene ID Mouse: | 19262 |
| Regulatory Statement: | For Research Use Only. Not for use in diagnostic procedures. |
| Product Type: | Protein |
| Shipping: | dry ice |
| Size: | 50 μg |
| Species Reactivities: | Human |
| Status: | RUO |
| Storage: | -70℃ |
| Target: | PTPRA |
Applications:
There are no references for Protein Tyrosine Phosphatase PTPRA 2nd Catalytic Domain(human recombinant, active) at this time.