Solutions for Life Science & Diagnostics
anti-cIAP-2/HIAP-1
Additional Information
anti-cIAP-2/HIAP-1 Specifications
| Background: | Apoptosis can be inhibited by a group of proteins called inhibitors of apoptosis (IAPs). These proteins contain a BIR (baculovirus IAP repeat) domain near the amino-terminus. The BIR domain can bind some caspases. Many members of the IAP family of proteins block proteolytic activation of caspase-3 and 7. For example, XIAP, cIAP-1, and cIAP-2 appear to block cytochrome c-induced activation of caspase-9, thereby preventing initiation of the caspase cascade. Since cIAP-1 and cIAP-2 were first identified as components in the cytosolic death domain-induced complex associated with the TNF family of receptors, they may inhibit apoptosis by additional mechanisms. The predicted molecular weight of cIAP-2 is 67 kDa. |
| Clonality: | Polyclonal |
| Host Species: | Rabbit |
| Regulatory Statement: | For Research Use Only. Not for use in diagnostic procedures. |
| Isotype: | IgG |
| Product Type: | Primary Antibody |
| Shipping: | 4 |
| Size: | 100 µg |
| Species Reactivities: | H,M,R |
| Status: | RUO |
| Storage: | -20℃ |
| Target: | cIAP-2/HIAP-1 |
Applications: WB
| WB: | 1-3 ug/mL |
There are no references for anti-cIAP-2/HIAP-1 at this time.
