Solutions for Life Science & Diagnostics

anti-Active Caspase-9

Ordering Guide

SKUNameSizeQtyPriceAdd to Cart
BV-3149-3 anti-Active Caspase-9 100 µg $486.68

Additional Information

anti-Active Caspase-9 Specifications

Background:Caspases are synthesized as inactive pro-enzymes that are processed to active form in cells undergoing apoptosis. Caspase-9 is an important member of the caspase family. Upon induction of apoptosis, Cytochrome c released from mitochondria associates with pro-caspase-9 (47 kDa) and Apaf-1. The complex processes pro-caspase-9 into a large subunit (37 kDa/17 kDa) and a small subunit (10 kDa). Cleaved caspase-9 further processes other caspases including caspase-3 and caspase-6, to initiate a caspase cascade leading to apoptosis. The affinity purified antibody recognizing the active forms of caspase-9 provides a new tool for identifying apoptotic cell populations in both tissue sections and cultured cells.
Host Species:Rabbit
Regulatory Statement:For Research Use Only. Not for use in diagnostic procedures.
Product Type:Primary Antibody
Size:100 µg
Species Reactivities:H

Applications: WB, IP, IC

ICC:10-20 ug/mL
IPP:10-20 ug/mL
WB:0.5-4 ug/mL

There are no references for anti-Active Caspase-9 at this time.