- Diagnostic Products
- Research Products
|Background:||Caspases are synthesized as inactive pro-enzymes that are processed to active form in cells undergoing apoptosis. Caspase-7 has been identified as a major contributor to the execution of apoptosis. Many enzymes, including caspase-3, -6, -8, -9 and granzyme B, cleave caspase-7. Active caspase-7 consists of a heterotetramer of two large and two small subunits. As an effector caspase, caspase-7 cleaves many of the same substrates as caspase-3, including poly (ADP-ribose) and polymerase (PARP). The active caspase-7 antibody provides a new tool for identifying apoptotic cell populations in both tissue sections and cultured cells.|
|Regulatory Statement:||For Research Use Only. Not for use in diagnostic procedures.|
|Product Type:||Primary Antibody|
Applications: WB, IP, IH
There are no references for anti-Active Caspase-7 at this time.