Solutions for Life Science & Diagnostics
anti-Active Caspase-7
Additional Information
anti-Active Caspase-7 Specifications
| Background: | Caspases are synthesized as inactive pro-enzymes that are processed to active form in cells undergoing apoptosis. Caspase-7 has been identified as a major contributor to the execution of apoptosis. Many enzymes, including caspase-3, -6, -8, -9 and granzyme B, cleave caspase-7. Active caspase-7 consists of a heterotetramer of two large and two small subunits. As an effector caspase, caspase-7 cleaves many of the same substrates as caspase-3, including poly (ADP-ribose) and polymerase (PARP). The active caspase-7 antibody provides a new tool for identifying apoptotic cell populations in both tissue sections and cultured cells. |
| Clonality: | Polyclonal |
| Host Species: | Rabbit |
| Regulatory Statement: | For Research Use Only. Not for use in diagnostic procedures. |
| Isotype: | IgG |
| Product Type: | Primary Antibody |
| Shipping: | 4 |
| Size: | 100 µg |
| Species Reactivities: | H,M,R |
| Status: | RUO |
| Storage: | -20℃ |
| Target: | caspase-7 |
Applications: WB, IP, IH
| IHC: | 10-20 ug/mL |
| IPP: | 10-20 ug/mL |
| WB: | 1 ug/mL |
There are no references for anti-Active Caspase-7 at this time.
