| Background: | The members of the solute carrier family 22 (SLC22) belong to the organic cation/anion/zwitterion transporter family. SLC22A5, which is also known as OCTN2, is expressed in the muscle, heart, and kidney. It is mainly involved in the transportation of carnitine in a sodium-dependent manner. Primary systemic carnitine deficiency is caused by mutations in the SLC22A5 gene. A mouse with a spontaneous mutation in the slc22a5 gene, which is designated as juvenile visceral steatosis (JVS), develops an enlarged fatty liver, steatosis of other organs, and hypertrophic cardiomyopathy, and eventually dies at 4 to 5 weeks unless carnitine is administered. Defects in SLC22A5/OCTN2 may also lead to increased susceptibility to Crohn’s disease. |
| Clonality: | Polyclonal |
| Gene ID Human: | 6584 |
| Gene ID Mouse: | 20520 |
| Host Species: | Rabbit |
| Regulatory Statement: | For Research Use Only. Not for use in diagnostic procedures. |
| Isotype: | IgG |
| Product Type: | Primary Antibody |
| Shipping: | 4 |
| Size: | 10μL |
| Status: | RUO |
| Storage: | -20 |
| Target: | SLC22A5/OCTN2 |
Applications:
There are no additional documents for Anti-SLC22A5/OCTN2 polyclonal antibody Trial size at this time.
There are no references for Anti-SLC22A5/OCTN2 polyclonal antibody Trial size at this time.