anti-SLC2A2/GLUT2

Code No: BMP070
Datasheet: 
Background: 

Members of the solute carrier family 2 are classified as facilitative glucose transporters (GLUTs), which transport glucose into most cells. SLC2A2/GLUT2 is predominantly expressed in the liver and weakly expressed in the kidney and small intestine. Mice in which the slc2a2 gene is deleted are hyperglycemic and hypoinsulinemic; they have elevated plasma levels of glucagons, free fatty acids, and -hydroxybutyrate. Truncated forms of SLC2A2/GLUT2 that result from gene mutation are detected in patients with Fanconi-Bickel syndrome; this condition is characterized by hepatorenal glycogen accumulation, proximal renal tubular dysfunction, and impaired carbohydrate metabolism, possibly caused by dysfunction of the truncated SLC2A2/GLUT2.

Size: 
100 μL
Application: 
FCM
Application: 
IHC
Product Type: 
Primary Antibody
Host Species: 
Rabbit
Species Reactivities: 
H
Isotype: 
Ig (aff.)
Storage Temp. (°C): 
4
Shipping Temp. (°C): 
-20
Pictures: 
anti-SLC2A2/GLUT2
anti-SLC2A2/GLUT2
References: 

Santer, R., et al., Hum. Genet. 110, 21-29 (2002)

Intended Use: 
For Research use only. Not for use in diagnostic procedure.