Anti-SLC6A8/CRTR polyclonal antibody Trial size

Code No: BMP047B
Gene/antigen ID number: 
6535
Target: 

SLC6A8/CRTR

Background: 

SLC6A8, also known as CRTR, CT1, or CRT, belongs to the Na+- and Cl–- dependent neurotransmitter transporter family and transports creatine in the brain and muscles. Since muscle cells do not synthesize creatine, they must take it up via SLC6A8. Missense mutations in the SLC6A8 gene result in the X-linked creatine deficiency syndrome, which is characterized by mental retardation and physical developmental disorders due to a defect in creatine metabolism.

Size: 
10μL
Application: 
FCM
Application: 
IC
Application: 
IHC
Application: 
WB
Clone Number: 
Polyclonal
Product Type: 
Primary Antibody
Host Species: 
Rabbit
Species Reactivities: 
Human
Isotype: 
IgG
Storage Temp. (°C): 
4
Shipping Temp. (°C): 
-20
References: 

Stockler, S., et al., Subcell Biochem. 46, 149-166 (2007) Schiaffino, M. C., et al., Neurogenetics 6, 165-168 (2005) Bizzi, A., et al., Ann. Neurol. 52, 227-231 (2002) Barnwell, L. F., et al., Gene 159, 287-288 (1995) Nash, S. R., et al., Receptors Channels 2, 165-174 (1994)

Formulation: 
50 uL volume of PBS containing 50% glycerol, pH 7.2. No preservative is contained.
Reactivity: 
This antibody can be used to stain endogenous antigen in paraffin embedded human tissues including kidney by Immunohistochemistry. The reactivity has been confirmed by Western blotting, Immunocytochemistry, and intracellular Flow cytometry to detect the full length of human SLC6A8 transiently expressed in HEK 293T cells.
Intended Use: 
For Research use only. Not for use in diagnostic procedure.