| Background: | SLC7A8, also called l-type amino acid transporter 2 (LAT2), forms a heterodimeric complex with the heavy chain of the cell surface antigen SLC3A2 (4F2hc/CD98). It transports neutral amino acids, most of which are essential amino acids. l-Dopa, which is commonly used to treat Parkinson’s disease, can enter the brain as either the SLC7A8 (LAT2)/SLC3A2 complex or as its homologue the SLC7A7 (LAT1)/SLC3A2 complex. Furthermore, SLC7A8 is highly expressed in the epithelial proximal tubule cells in the kidney; this suggests its role in renal reabsorption of neutral amino acids. |
| Clonality: | Polyclonal |
| Gene ID Human: | 23428 |
| Gene ID Mouse: | 50934 |
| Host Species: | Rabbit |
| Regulatory Statement: | For Research Use Only. Not for use in diagnostic procedures. |
| Isotype: | IgG |
| Product Type: | Primary Antibody |
| Shipping: | 4 |
| Size: | 10μL |
| Status: | RUO |
| Storage: | -20 |
| Target: | SLC7A8 |
Applications:
There are no additional documents for Anti-SLC7A8/LAT2 polyclonal antibody Trial size at this time.
There are no references for Anti-SLC7A8/LAT2 polyclonal antibody Trial size at this time.