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|Background:||SLC7A8, also called l-type amino acid transporter 2 (LAT2), forms a heterodimeric complex with the heavy chain of the cell surface antigen SLC3A2 (4F2hc/CD98). It transports neutral amino acids, most of which are essential amino acids. l-Dopa, which is commonly used to treat Parkinsonâ€™s disease, can enter the brain as either the SLC7A8 (LAT2)/SLC3A2 complex or as its homologue the SLC7A7 (LAT1)/SLC3A2 complex. Furthermore, SLC7A8 is highly expressed in the epithelial proximal tubule cells in the kidney; this suggests its role in renal reabsorption of neutral amino acids.|
|Gene ID Human:||23428|
|Gene ID Mouse:||50934|
|Regulatory Statement:||For Research Use Only. Not for use in diagnostic procedures.|
|Product Type:||Primary Antibody|
There are no additional documents for Anti-SLC7A8/LAT2 polyclonal antibody Trial size at this time.
There are no references for Anti-SLC7A8/LAT2 polyclonal antibody Trial size at this time.