SLC2A5/GLUT5 polyclonal antibody

Code No: BMP034
Target: 

SLC2A5/GLUT5

Background: 

SLC2A5, also known as glucose transporter type 5 (GLUT5), belongs to the facilitative glucose/fructose transporter family and plays a role in the uptake of fructose in the small intestine and kidney. A high fructose diet enhances the expression of SLC2A5 in the small intestine of mice. Increased fructose consumption is associated with many aspects of the metabolic syndrome, such as hypertension, insulin resistance, and dyslipidemia. Thus, SLC2A5 and related transporter genes, including SLC26A6, are suspected to play a role in various metabolic disorders. SLC2A5 is also found in mature spermatozoa and is suggested to be a reliable indicator of terminal maturation of male germ cells in the testis.

Size: 
50 uL
Application: 
WB
Application: 
FCM
Application: 
IC
Application: 
IHC
Clone Number: 
Polyclonal
Product Type: 
Primary Antibody
Host Species: 
Rabbit
Species Reactivities: 
Human
Storage Temp. (°C): 
-20
Shipping Temp. (°C): 
4
References: 

1) Singh, A. K., et al., Kidney Int. 74, 438-447 (2008)
2) Douard, V, and Ferraris, R. P., Am. J. Physiol. Endocrinol. Metab. 295, E227-E237 (2008)
3) Davidson, N. O., et al., Am. J. Physiol. 262, C795-C800 (1992)
4) Kayano, T. J., et al., Biol. Chem. 265, 13276-13282 (1990)

Formulation: 
50 uL volume of PBS containing 50% glycerol, pH 7.2. No preservative is contained.
Reactivity: 
This antibody can be used to stain endogenous antigen in paraffin embedded human tissues including small intestine and testis by Immunohistochemistry. The reactivity has been confirmed by Western blotting, Immunocytochemistry, and intracellular Flow cytometry to detect the full length of human SLC2A5 transiently expressed in HEK 293T cells
Intended Use: 
For Research use only. Not for use in diagnostic procedure.