SLC9A1 Polyclonal Antibody
Code No: BMP023
Datasheet:
FID:3810 | PATH:sites/default/files/datasheets/BMP023.PDF
Background:
SLC9A1 (NHE1), a member of the Na+/H+ exchanger family, is a ubiquitous membrane protein that regulates intracellular pH and cell volume. Furthermore, SLC9A1 is known to interact with the actin cytoskeleton. Fibroblasts expressing mutated NHE1 that fails to interact with actin-related proteins show impaired organization of focal adhesion points and actin stress fibers, and an irregular cell shape. Polymorphisms of the SLC9A1 gene have been reported in association with essential hypertension.
Product Type:
Primary Antibody
Species Reactivities:
Human
Related Products:
BMP023 anti-SLC9A1/NHE1 (polyclonal)
BMP049 anti-SLC9A6/NHE6 (polyclonal) 091023-2
References:
1) Denker, S. P., et al., Mol Cell 6, 1425-1436 (2000)
2) Dudley, C. R., et al., Hum Genet 86, 79-83 (1990)
3) Sardet, C., et al., Cell 56, 271-280 (1989).
Formulation:
100 uL volume of PBS containing 50% glycerol, pH 7.2. No preservative is contained.
Reactivity:
This antibody can be used to stain endogenous antigen in paraffin embedded human tissues including stomach and kidney by immunohistochemistry. The reactivity of this antibody has been confirmed by Western blotting, Immunocytochemistry and Flow cytometry to detect the full-length of human SLC9A1 transiently expressed in HEK 293T cells.
Intended Use:
For Research use only. Not for use in diagnostic procedure.
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