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|Background:||SLC6A3, also known as DAT1, is a transporter for the neurotransmitter dopamine. SLC6A3 regulates dopamine homeostasis by reuptaking dopamine released into the synaptic cleft. SLC6A3 polymorphisms are associated with nicotine addiction, especially cessation attempts from individual cigarette smoking. Polymorphisms in the SLC6A3 gene have also been reported to constitute one cause for Attention-deficit hyperactivity disorder (ADHD), the most common childhood-onset behavioral disorder.|
|Gene ID Human:||6531|
|Gene ID Mouse:||13162|
|Regulatory Statement:||For Research Use Only. Not for use in diagnostic procedures.|
|Product Type:||Primary Antibody|
|Reactivity:||This antibody can be used to stain endogenous antigen in paraffin embedded human tissues including brain and Peyer’s patches in large intestine by immunohistochemistry. The reactivity of this antibody has been confirmed by Western blotting to detect the f|
|Source:||This antibody was affinity purified from rabbit serum. The rabbit was immunized with a synthetic peptide derived from human SLC6A3.|
There are no additional documents for Anti-SLC6A3/DAT1 polyclonal antibody Trial size at this time.
1) Feng, Y., et al., Am. J. Med. Genet. 139B, 1-6 (2005) 2) Lerman, C., et al., Health Psych. 18, 14-20 (1999) 3) Sabol, S. Z., et al., Health Psych. 18, 7-13 (1999) 4) Waldman, I. D. et al., Am. J. Hum. Genet. 63, 1767-1776 (1998) 5) Cook, E. H., et al.