Solutions for Life Science & Diagnostics
Anti-SLC4A1/AE1 polyclonal antibody Trial size
Additional Information
Anti-SLC4A1/AE1 polyclonal antibody Trial size Specifications
| Background: | SLC4A1/AE1/Band3/CD233, a member of the anion exchanger family, is the major glycoprotein of the erythrocyte membrane. SLC4A1 has an important role for the high rate exchange of chloride by bicarbonate ion during carbon dioxide transport by erythrocytes. Defective mutations of SLC4A1 gene have been reported to cause either the erythroid disorders including spherocytic hemolytic anaemia or ovalocytosis, or distal renal tubular acidosis. One SLC4A1 null human is also known with very severe anemia and nephrocalcinosis. |
| Clonality: | Polyclonal |
| Gene ID Human: | 6521 |
| Gene ID Mouse: | 20533 |
| Host Species: | Rabbit |
| Regulatory Statement: | For Research Use Only. Not for use in diagnostic procedures. |
| Isotype: | IgG |
| Product Type: | Primary Antibody |
| Reactivity: | This antibody can be used to stain erythrocytes in paraffin embedded human tissues by immunohistochemistry. The reactivity of this antibody has been confirmed by Western blotting to detect the full-length of human SLC4A1 transiently expressed in HEK 293T |
| Shipping: | 4 |
| Size: | 10μL |
| Source: | This antibody was affinity purified from rabbit serum. The rabbit was immunized with a synthetic peptide derived from human SLC4A1. |
| Status: | RUO |
| Storage: | -20 |
| Target: | SLC4A1/AE1 |
Applications:
There are no additional documents for Anti-SLC4A1/AE1 polyclonal antibody Trial size at this time.
1) Shayakul, C., and Alper, S. L., Clin. Exp. Nephrol. 8, 1-11 (2004) 2) Karet, F. E., et al., PNAS 95, 6337-6342 (1998) 3) Lux, S. E., et al., PNAS 86, 9089-9093 (1989) 4) Palumbo, A. P., et al., Am. J. Hum. Genet. 39, 307-316 (1986)
