Phospho-Lck [Tyr192] Polyclonal Antibody
Phospho-Lck [Tyr192] Polyclonal Antibody Specifications
|Background:||Lck (p56lck), a member of the Src family of non-receptor tyrosine protein kinases, is expressed predominantly in T-cells. Lck function is critical for both T-cell development in the thymus and activation of mature T-cells in the periphery by antigen. The activity of Lck is regulated by phosphorylation of multiple sites, including the two conserved residues, tyrosines 394 (equivalent to 418 in Src) and 505 (equivalent to 529 in Src). Phosphorylation of tyrosine 192 by Syk promotes activation of Lck by preventing the binding of the negative regulatory site, tyrosine 505.
|Regulatory Statement:||For Research Use Only. Not for use in diagnostic procedures.|
|Product Type:||Primary Antibody|
There are no references for Phospho-Lck [Tyr192] Polyclonal Antibody at this time.