Solutions for Life Science & Diagnostics

Phospho-EGFR [Tyr1148] Polyclonal Antibody

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SKUNameSizeQtyPriceAdd to Cart
AT-7148 Phospho-EGFR [Tyr1148] Polyclonal Antibody 100 µL $374.74

Additional Information

Phospho-EGFR [Tyr1148] Polyclonal Antibody Specifications

Background:Epidermal Growth Factor Receptor, also known as ErbB-1 (EGFR, a 185 kDa glycoprotein) is a transmembrane tyrosine kinase that regulates a variety of biological responses ranging from mitogenesis to stress signaling. The EGFR consists of a large extracellular domain, a single transmembrane domain and a cytoplasmic domain that exhibits kinase activity. Upon binding of EGF to the extracellular domain, the receptor undergoes dimerization and becomes phosphorylated on several tyrosine residues within the cytoplasmic domain, one of which is tyrosine 1148. This results in EGFR activation and increased tyrosine kinase activity toward a variety of intracellular substrates.
Host Species:Rabbit
Regulatory Statement:For Research Use Only. Not for use in diagnostic procedures.
Product Type:Primary Antibody
Size:100 µL
Species Reactivities:H
Target:Phospho-EGFR [Tyr1148]

Applications: WB

There are no references for Phospho-EGFR [Tyr1148] Polyclonal Antibody at this time.