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Phospho-PAG3 [Tyr724] Polyclonal Antibody

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AT-7143 Phospho-PAG3 [Tyr724] Polyclonal Antibody 100 µL $363.83

Additional Information

Phospho-PAG3 [Tyr724] Polyclonal Antibody Specifications

Background:PAG3 (paxillin-associated protein with ADP-ribosylation factor [ARF] GTPase-activating protein [GAP] activity, number 3) is a member of the ARF GAP family of proteins that associates with the cytoskeleton, plays an important role in mediating actin cytoskeletal organization in response to adhesion and growth factor stimulation, and is involved in paxillin subcellular localization. During monocyte maturation, the elevation of paxillin expression and integrin activation is associated with the induction of PAG3 expression. Overexpression of PAG3 inhibits paxillin recruitment to focal contacts and hinders cellular migration. PAG3 is phosphorylated by Pyk2 kinase on tyrosines 724 and 763.
Host Species:Rabbit
Regulatory Statement:For Research Use Only. Not for use in diagnostic procedures.
Product Type:Primary Antibody
Size:100 µL
Species Reactivities:H
Target:Phospho-PAG3 [Tyr724]

Applications: WB

There are no references for Phospho-PAG3 [Tyr724] Polyclonal Antibody at this time.