Solutions for Life Science & Diagnostics
Phospho-PLC gamma-1 [Tyr783] Polyclonal Antibody
Additional Information
Phospho-PLC gamma-1 [Tyr783] Polyclonal Antibody Specifications
| Background: | Phosphoinositide-specific phospholipase C (PLC) is a family of proteins that hydrolyze phosphatidylinositol 4,5-bisphosphate to generate the second messengers, inositol 1,4,5- trisphosphate (IP3) and diacylglycerol (DAG). IP3 induces a transient increase in intracellular free Ca2+, while DAG is a direct activator of protein kinase C (PKC). These processes are involved in the control of multiple cellular activities such as cell proliferation, growth and differentiation. PLCï§-1 is a 135 kDa ubiquitously expressed isozyme that is activated by phosphorylation of tyrosine 783 and interacts with growth factor receptors (EGFR, PDGFR, etc.) and adhesion/ cytoskeletal proteins (FAK, paxillin) to influence a multiple number of signaling pathways. |
| Clonality: | Polyclonal |
| Host Species: | Rabbit |
| Regulatory Statement: | For Research Use Only. Not for use in diagnostic procedures. |
| Isotype: | IgG |
| Product Type: | Primary Antibody |
| Shipping: | 4 |
| Size: | 100 µL |
| Species Reactivities: | H, M |
| Status: | RUO |
| Storage: | -20 |
| Target: | Phospho-PLC gamma-1 [Tyr783] |
Applications: WB, IH
There are no references for Phospho-PLC gamma-1 [Tyr783] Polyclonal Antibody at this time.
