Solutions for Life Science & Diagnostics

Phospho-PLC gamma-1 [Tyr783] Polyclonal Antibody

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AT-7142 Phospho-PLC gamma-1 [Tyr783] Polyclonal Antibody 100 µL $363.83

Additional Information

Phospho-PLC gamma-1 [Tyr783] Polyclonal Antibody Specifications

Background:Phosphoinositide-specific phospholipase C (PLC) is a family of proteins that hydrolyze phosphatidylinositol 4,5-bisphosphate to generate the second messengers, inositol 1,4,5- trisphosphate (IP3) and diacylglycerol (DAG). IP3 induces a transient increase in intracellular free Ca2+, while DAG is a direct activator of protein kinase C (PKC). These processes are involved in the control of multiple cellular activities such as cell proliferation, growth and differentiation. PLC-1 is a 135 kDa ubiquitously expressed isozyme that is activated by phosphorylation of tyrosine 783 and interacts with growth factor receptors (EGFR, PDGFR, etc.) and adhesion/ cytoskeletal proteins (FAK, paxillin) to influence a multiple number of signaling pathways.
Host Species:Rabbit
Regulatory Statement:For Research Use Only. Not for use in diagnostic procedures.
Product Type:Primary Antibody
Size:100 µL
Species Reactivities:H, M
Target:Phospho-PLC gamma-1 [Tyr783]

Applications: WB, IH

There are no references for Phospho-PLC gamma-1 [Tyr783] Polyclonal Antibody at this time.