| Background: | Focal Adhesion Kinase (FAK) is a 125 kDa non-receptor protein tyrosine kinase that is a substrate for Src and a key element in growth factor and integrin signaling. FAK plays a central role in cell spreading, differentiation, migration, cell death and acceleration of the G1 to S phase transition of the cell cycle. Tyrosine 861 of FAK is a major Src phosphorylation site that promotes the binding of FAK to the cytoplasmic tail integrins, and is also involved in cancer. |
| Clonality: | Polyclonal |
| Host Species: | Rabbit |
| Regulatory Statement: | For Research Use Only. Not for use in diagnostic procedures. |
| Isotype: | IgG |
| Product Type: | Primary Antibody |
| Shipping: | 4 |
| Size: | 100 µL |
| Species Reactivities: | H, M, ch |
| Status: | RUO |
| Storage: | -20 |
| Target: | Phospho-FAK [Tyr861] |
Applications: WB, IH
There are no references for Phospho-FAK [Tyr861] Polyclonal Antibody at this time.