Solutions for Life Science & Diagnostics
Phospho-MEK1 [Ser298] Polyclonal Antibody
Additional Information
Phospho-MEK1 [Ser298] Polyclonal Antibody Specifications
| Background: | Microtubule-associated protein kinase kinase 1 (MEK1 or MAPKK1) is a member of a family of tyrosine/threonine protein kinases that activate the ERK1&2/MAPK enzymes by phosphorylating both residues within the threonine – glutamic acid – tyrosine (TEY) motif in the activation loop. MEK1&2 are also activated by dual-phosphorylation, which occurs on serines 218 and 222, in the activation loop of the MEKs. Serine 298 of MEK1 is phosphorylated by PAK proteins, which promote MEK1 binding to c-Raf and its subsequent phosphorylation of MEK1, leading to activation of the MAPK pathway. |
| Clonality: | Polyclonal |
| Host Species: | Rabbit |
| Regulatory Statement: | For Research Use Only. Not for use in diagnostic procedures. |
| Isotype: | IgG |
| Product Type: | Primary Antibody |
| Shipping: | 4 |
| Size: | 100 µL |
| Species Reactivities: | H, M, R |
| Status: | RUO |
| Storage: | -20 |
| Target: | Phospho-MEK1 [Ser298] |
Applications: WB
There are no references for Phospho-MEK1 [Ser298] Polyclonal Antibody at this time.
