Solutions for Life Science & Diagnostics

Phospho-MEK1 [Ser298] Polyclonal Antibody

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SKUNameSizeQtyPriceAdd to Cart
AT-7108 Phospho-MEK1 [Ser298] Polyclonal Antibody 100 µL $363.83

Additional Information

Phospho-MEK1 [Ser298] Polyclonal Antibody Specifications

Background:Microtubule-associated protein kinase kinase 1 (MEK1 or MAPKK1) is a member of a family of tyrosine/threonine protein kinases that activate the ERK1&2/MAPK enzymes by phosphorylating both residues within the threonine – glutamic acid – tyrosine (TEY) motif in the activation loop. MEK1&2 are also activated by dual-phosphorylation, which occurs on serines 218 and 222, in the activation loop of the MEKs. Serine 298 of MEK1 is phosphorylated by PAK proteins, which promote MEK1 binding to c-Raf and its subsequent phosphorylation of MEK1, leading to activation of the MAPK pathway.
Host Species:Rabbit
Regulatory Statement:For Research Use Only. Not for use in diagnostic procedures.
Product Type:Primary Antibody
Size:100 µL
Species Reactivities:H, M, R
Target:Phospho-MEK1 [Ser298]

Applications: WB

There are no references for Phospho-MEK1 [Ser298] Polyclonal Antibody at this time.