Solutions for Life Science & Diagnostics

beta-Amyloid (Abeta) (pan) Polyclonal Antibody

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SKUNameSizeQtyPriceAdd to Cart
AT-5001 beta-Amyloid (Abeta) (pan) Polyclonal Antibody 100 µg $409.50

Additional Information

beta-Amyloid (Abeta) (pan) Polyclonal Antibody Specifications

Background:Alzheimerï¾’s disease (AD) is the most common form of dementia in the elderly. The neuropathological hallmarks are neurofibrillary tangles and senile plaques. The major protein component of the plaques is a 39-42 amino acid peptide (?-amyloid/A?). A? occurs in two predominant forms with different COOH-termini, A? 40 and A? 42, and overproduction of A? 42 has been suggested to be the cause of familial early-onset AD. A? generation depends on proteolytic cleavage of the amyloid precursor protein (APP) by two unknown proteases: ?-secretase and ?-secretase. Recent studies suggest that a transmembrane aspartic protease, termed beta-site APP-cleaving enzyme (BACE), functionally acts as the ?-secretase.
Clonality:Polyclonal
Host Species:Rabbit
Regulatory Statement:For Research Use Only. Not for use in diagnostic procedures.
Isotype:IgG
Product Type:Primary Antibody
Shipping:4
Size:100 µg
Species Reactivities:H
Status:RUO
Storage:-20
Target:beta-Amyloid

Applications: IH, ELISA

There are no references for beta-Amyloid (Abeta) (pan) Polyclonal Antibody at this time.